Profundus Imaging

Pioneering eye diagnostics with telescope technology

The Profundus Guide Star System - a new product to meet the increasing need for imaging microstructures of the retina.

A major problem in wide-field retinal imaging is the angular dependence of many optical aberrations of the eye, a property shared by most optical systems. This is currently overcome by using a small imaging field, which makes imaging of larger contiguous retinal areas a time-consuming process.

The Profundus Guide Star System was developed from the first experimental retinal imaging evaluation, using two deformable mirrors, to increase the corrected field-of-view. This anables an improved imaging process with high resolution over wider imaging fields. 

The Profundus Guide Star System has been optimized and miniaturized into a desktop proof-of-concept prototype that has been designed for clinical use.


The general principle of AO in the eye

A probe beam is focused to a spot on the retina. The reflected light from this retinal beacon will radiate through the optical media (basically the cornea and the lens) and the pupil of the eye. A wavefront sensor is used to measure the aberrations introduced by the optics of the eye, and a control computer is used to analyze the measurements and calculate a correction.

High-resolution imaging of the object is enabled by applying the calculated corrections to a corrective element, usually a deformable mirror, positioned in a pupil conjugate plane in the optical path between the retina and its image on the retinal camera.

Such a system is referred to as a single-conjugate AO system. Retinal features down to a few microns can be resolved by correcting the optical imperfections of the eye.

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